Acetone → 3-(5-broMopyridin-2-yl)propanoic acid

HRID 950142Notes

Reaction equation

HRID 950142 reaction equation
[Br-:13].[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][CH2:10][OH:11])[n:6][cH:7]1.[C:37](=[O:38])([OH:39])[O-:40].[CH3:14][C:15]1([CH3:24])[N:16]([O:17])[C:18]([CH3:19])([CH3:20])[CH2:21][CH2:22][CH2:23]1.[CH3:42][C:43](=[O:44])[CH3:45].[Cl:25][n:26]1[c:27](=[O:32])[n:28]([Cl:29])[c:30](=[O:31])[n:33]([Cl:34])[c:35]1=[O:36].[Na+:12].[Na+:41]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][C:10](=[O:11])[OH:32])[n:6][cH:7]1

Participants

8

Reactant 7

HCID 180AcetoneHCID 259Bromide ionHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6909Trichloroisocyanuric AcidHCID 5499762,2,6,6-Tetramethylpiperidin-1-olHCID 139797355-Bromo-2-pyridinepropanol

Product 1

HCID 686729443-(5-broMopyridin-2-yl)propanoic acid

Sources & evidence

ORD record
ord-3b68972734a74828ae756faa71078bef
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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