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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950204Generated: October 27, 2026

Dimethylformamide → N-(3-Fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-yl)ethoxy)pyrrolo[2,1-f][1,2,4]triazin-4-yloxy)phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

https://huagongshe.com/reaction/950204

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
Reactant1-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acidHCID 21081527—
Reactant3-Fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-yl)ethoxy)pyrrolo[2,1-f][1,2,4]triazin-4-yloxy)benzenamineHCID 21081609—
ProductN-(3-Fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-yl)ethoxy)pyrrolo[2,1-f][1,2,4]triazin-4-yloxy)phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamideHCID 16112844—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d07d4aed2e164f0bbcbb5c712e679388
Source noteValidation data from https://doi.org/10.1039/C8SC04228D