6-(4-oxocyclohexyl)-1,3-benzoxazol-2(3H)-one → 6-{trans-4-[3-(2,4-Difluorophenyl)propylamino]cyclohexyl}-3H-benzoxazol-2-one
Reaction equation
[CH:1]1([c:8]2[cH:9][c:10]3[c:11]([nH:12][c:13](=[O:15])[o:14]3)[cH:16][cH:17]2)[CH2:2][CH2:3][C:4](=[O:7])[CH2:5][CH2:6]1.[F:18][c:19]1[c:20]([CH2:26][CH2:27][CH2:28][NH2:29])[cH:21][cH:22][c:23]([F:25])[cH:24]1>>[CH:1]1([c:8]2[cH:9][c:10]3[c:11]([nH:12][c:13](=[O:15])[o:14]3)[cH:16][cH:17]2)[CH2:2][CH2:3][CH:4]([NH:29][CH2:28][CH2:27][CH2:26][c:20]2[c:19]([F:18])[cH:24][c:23]([F:25])[cH:22][cH:21]2)[CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-3e8758bc3bad469d8d190a39cae0fd6f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…