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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950328Generated: October 27, 2026

Dimethylformamide → 5-Chloro-4-(1-(5-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one

https://huagongshe.com/reaction/950328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
Reactantethyl N-ethoxycarbonyliminocarbamateHCID 220568—
ReactantGimeracilHCID 54679224—
Reactant1-(5-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-olHCID 57708429—
Product5-Chloro-4-(1-(5-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-oneHCID 58467950—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3b00e32d050c4a328cf1c7f0128e02b5
Source noteValidation data from https://doi.org/10.1039/C8SC04228D