N-{3-tert-Butyl-1-[4-(2-methoxyethoxy)phenyl]-1H-pyrazol-5-yl}-N'-[4-(pyridin-4-yloxy)-phenyl]urea → N-{3-tert-Butyl-1-[4-(2-methoxyethoxy)phenyl]-1H-pyrazol-5-yl}-N'-{2-fluoro-4-[(2-methylpyridin-4-yl)oxy]phenyl}urea
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:21][C:22](=[O:23])[NH:24][c:25]2[cH:26][cH:27][c:28]([O:29][c:30]3[cH:31][cH:32][n:33][cH:34][cH:35]3)[cH:36][cH:37]2)[n:8](-[c:10]2[cH:11][cH:12][c:13]([O:16][CH2:17][CH2:18][O:19][CH3:20])[cH:14][cH:15]2)[n:9]1.[F:38][c:39]1[c:40]([NH2:53])[cH:41][cH:42][c:43]([O:45][c:46]2[cH:47][c:48]([CH3:52])[n:49][cH:50][cH:51]2)[cH:44]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:21][C:22](=[O:23])[NH:53][c:40]2[c:39]([F:38])[cH:44][c:43]([O:45][c:46]3[cH:47][c:48]([CH3:52])[n:49][cH:50][cH:51]3)[cH:42][cH:41]2)[n:8](-[c:10]2[cH:11][cH:12][c:13]([O:16][CH2:17][CH2:18][O:19][CH3:20])[cH:14][cH:15]2)[n:9]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5688c621d3494999a6f595c3be173561
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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