3-Chlorobenzo(b)thiophene-2-carbonyl chloride → tert-Butyl {4-[(3-chloro-benzo[b]thiophene-2-carbonyl)-(4,4'-dimethoxy-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate
Reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:17][NH:18][CH:19]2[CH2:20][CH2:21][CH:22]([N:25]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH3:33])[CH2:23][CH2:24]2)[cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:7][cH:8]1.[Cl:34][c:35]1[c:36]2[c:37]([s:38][c:39]1[C:40](=[O:41])[Cl:42])[cH:43][cH:44][cH:45][cH:46]2>>[CH3:1][O:2][c:3]1[c:4]([CH2:17][N:18]([CH:19]2[CH2:20][CH2:21][CH:22]([N:25]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH3:33])[CH2:23][CH2:24]2)[C:40]([c:39]2[c:35]([Cl:34])[c:36]3[c:37]([s:38]2)[cH:43][cH:44][cH:45][cH:46]3)=[O:41])[cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:7][cH:8]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-974ce856ca6341b88f7f214be21694a3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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