2-Chloropyridine-4-boronic acid → 2-(2-Chloro-pyridin-4-yl)-4-(3,4-difluoro-phenyl)-6-trifluoromethyl-pyrimidine

HRID 950543Notes

Reaction equation

HRID 950543 reaction equation
[Cl:1][c:2]1[n:3][c:4](-[c:12]2[cH:13][c:14]([F:19])[c:15]([F:18])[cH:16][cH:17]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1.[Cl:20][c:21]1[n:22][cH:23][cH:24][c:25]([B:27]([OH:28])[OH:29])[cH:26]1>>[c:2]1(-[c:25]2[cH:24][cH:23][n:22][c:21]([Cl:20])[cH:26]2)[n:3][c:4](-[c:12]2[cH:13][c:14]([F:19])[c:15]([F:18])[cH:16][cH:17]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1

Participants

3

Reactant 2

HCID 51515952-Chloropyridine-4-boronic acidHCID 574686682-Chloro-4-(3,4-difluoro-phenyl)-6-trifluoromethyl-pyrimidine

Product 1

HCID 574688132-(2-Chloro-pyridin-4-yl)-4-(3,4-difluoro-phenyl)-6-trifluoromethyl-pyrimidine

Sources & evidence

ORD record
ord-7f856fc6ef4a4d8ebda920e495ed1d7c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…