2-Chloro-4-methoxybenzeneboronic acid → Benzyl 3-[[5-(2-chloro-4-methoxyphenyl)-3,6-diethylpyrazin-2-yl]amino]-4-hydroxypyrrolidine-1-carboxylate
Reaction equation
[Br:30][c:31]1[n:32][c:33]([CH2:56][CH3:57])[c:34]([NH:39][CH:40]2[CH2:41][N:42]([C:46](=[O:47])[O:48][CH2:49][c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[CH2:43][CH:44]2[OH:45])[n:35][c:36]1[CH2:37][CH3:38].[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[CH2:23][CH:24]2[OH:25])[n:26][c:27]1[CH2:28][CH3:29].[Cl:58][c:59]1[c:60]([B:67]([OH:68])[OH:69])[cH:61][cH:62][c:63]([O:65][CH3:66])[cH:64]1>>[c:31]1(-[c:60]2[c:59]([Cl:58])[cH:64][c:63]([O:65][CH3:66])[cH:62][cH:61]2)[n:32][c:33]([CH2:56][CH3:57])[c:34]([NH:39][CH:40]2[CH2:41][N:42]([C:46](=[O:47])[O:48][CH2:49][c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[CH2:43][CH:44]2[OH:45])[n:35][c:36]1[CH2:37][CH3:38]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0f4eccda3a9f4ba7a81b0cfc3d6ed958
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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