Acetone → 4-Chloro-6-cyclopropylamino-2-diethylamino-5-pyrimidinecarbonitrile
Reaction equation
[CH3:20][C:21](=[O:22])[CH3:23].[CH:16]1([NH2:19])[CH2:17][CH2:18]1.[Cl:1][c:2]1[n:3][c:4]([N:11]([CH2:12][CH3:13])[CH2:14][CH3:15])[n:5][c:6]([Cl:10])[c:7]1[C:8]#[N:9]>>[c:2]1([NH:19][CH:16]2[CH2:17][CH2:18]2)[n:3][c:4]([N:11]([CH2:12][CH3:13])[CH2:14][CH3:15])[n:5][c:6]([Cl:10])[c:7]1[C:8]#[N:9]Participants
4
Sources & evidence
- ORD record
- ord-6ceed475979842f2bec79ec2438de3aa
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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