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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950875Generated: October 26, 2026

Toluene → 1-(4-(6-Nitropyridin-3-YL)piperazin-1-YL)ethan-1-one

https://huagongshe.com/reaction/950875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
Reactant1-AcetylpiperazineHCID 83795—
ReactantDibenzylidene acetoneHCID 95417—
ReactantCesium cationHCID 104967—
ReactantBinap, (A+-)-HCID 634876—
Reactant5-Bromo-2-nitropyridineHCID 817620—
Product1-(4-(6-Nitropyridin-3-YL)piperazin-1-YL)ethan-1-oneHCID 4780686—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bf814f8f065e4066a37b49c2008b6fe6
Source noteValidation data from https://doi.org/10.1039/C8SC04228D