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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950903Generated: October 25, 2026

Hydrochloric Acid → N-[[5-(1,1-difluoroethyl)-2-(trifluoromethoxy)phenyl]methyl]-2-phenylpiperidin-3-amine

https://huagongshe.com/reaction/950903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantEthyl AcetateHCID 8857—
ReactantTert-butyl 3-[[5-(1,1-difluoroethyl)-2-(trifluoromethoxy)phenyl]methylamino]-2-phenylpiperidine-1-carboxylateHCID 18677607—
ProductN-[[5-(1,1-difluoroethyl)-2-(trifluoromethoxy)phenyl]methyl]-2-phenylpiperidin-3-amineHCID 18677617—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-064abaff1e5745e48efc9949b5c659bc
Source noteValidation data from https://doi.org/10.1039/C8SC04228D