1-Butanol → tert-butyl N-[1-[5-bromo-3-[(2-fluoro-5-methylbenzoyl)amino]-1H-pyrrolo[2,3-b]pyridin-4-yl]piperidin-3-yl]carbamate
Reaction equation
[Br:1][c:2]1[c:3]([F:22])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12]([c:13]1[c:14]([F:20])[cH:15][cH:16][c:17]([CH3:19])[cH:18]1)=[O:21].[CH2:37]([OH:38])[CH2:39][CH2:40][CH3:41].[NH:23]1[CH2:24][CH:25]([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:26][CH2:27][CH2:28]1>>[Br:1][c:2]1[c:3]([N:23]2[CH2:24][CH:25]([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:26][CH2:27][CH2:28]2)[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12]([c:13]1[c:14]([F:20])[cH:15][cH:16][c:17]([CH3:19])[cH:18]1)=[O:21]Participants
4
Sources & evidence
- ORD record
- ord-d0a473dd75a845778bc9390beaac190c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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