Dichloromethane → tert-butyl 2-oxo-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undec-3-ene-9-carboxylate
Reaction equation
[CH2:1]([CH:2]=[CH2:3])[C:4]1([N:17]([C:18]([CH:19]=[CH2:20])=[O:21])[CH2:22][c:23]2[c:24]3[cH:25][cH:26][n:27]([S:32](=[O:33])(=[O:34])[c:35]4[cH:36][cH:37][c:38]([CH3:39])[cH:40][cH:41]4)[c:28]3[cH:29][cH:30][cH:31]2)[CH2:5][CH2:6][N:7]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:8][CH2:9]1.[Cl:42][CH2:43][Cl:44]>>[CH2:1]1[CH:2]=[CH:3][C:18](=[O:21])[N:17]([CH2:22][c:23]2[c:24]3[cH:25][cH:26][n:27]([S:32](=[O:33])(=[O:34])[c:35]4[cH:36][cH:37][c:38]([CH3:39])[cH:40][cH:41]4)[c:28]3[cH:29][cH:30][cH:31]2)[C:4]12[CH2:5][CH2:6][N:7]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:8][CH2:9]2Participants
3
Sources & evidence
- ORD record
- ord-727907e90a244b21bfeb5367ec0b1168
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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