1-(2,6-dichlorophenyl)-3,4-dihydro-5-(4-fluoro-2-methylphenyl)-7-methoxy-2(1H)-quinolinone → 1-(2,6-Dichlorophenyl)-3,4-dihydro-5-(4-fluoro-2-methylphenyl)-7-hydroxy-2(1H)-quinolinone

HRID 951055Notes

Reaction equation

HRID 951055 reaction equation
[Cl:1][c:2]1[c:3]([N:9]2[C:10](=[O:29])[CH2:11][CH2:12][c:13]3[c:14](-[c:21]4[c:22]([CH3:28])[cH:23][c:24]([F:27])[cH:25][cH:26]4)[cH:15][c:16]([O:19][CH3:20])[cH:17][c:18]32)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[Cl:30][c:31]1[cH:32][cH:33][cH:34][c:35]([Cl:36])[c:37]1[N:38]1[c:39]2[c:40]([c:41](-[c:42]3[cH:43][cH:44][c:45]([F:46])[cH:47][c:48]3[F:49])[cH:50][c:51]([OH:52])[cH:53]2)[CH2:54][CH2:55][C:56]1=[O:57]>>[Cl:1][c:2]1[c:3]([N:9]2[C:10](=[O:29])[CH2:11][CH2:12][c:13]3[c:14](-[c:21]4[c:22]([CH3:28])[cH:23][c:24]([F:27])[cH:25][cH:26]4)[cH:15][c:16]([OH:19])[cH:17][c:18]32)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 226479211-(2,6-dichlorophenyl)-3,4-dihydro-5-(4-fluoro-2-methylphenyl)-7-methoxy-2(1H)-quinolinoneHCID 226480931-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-3,4-dihydro-7-hydroxy-2(1H)-quinolinone

Product 1

HCID 226480121-(2,6-Dichlorophenyl)-3,4-dihydro-5-(4-fluoro-2-methylphenyl)-7-hydroxy-2(1H)-quinolinone

Sources & evidence

ORD record
ord-bc3b02526bad4010a49da040da527606
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…