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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951057Generated: November 1, 2026

Ethanol → 4-[(2-{[4-(1,3-Thiazol-2-yl)phenyl]oxy}ethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/951057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantSodium ionHCID 923—
ReactantNitrogenHCID 947—
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantCarbonate IonHCID 19660—
Reactant2-BromothiazoleHCID 76430—
Reactant4-[(2-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]oxy}ethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 86623735—
ReactantHCID 178420554HCID 178420554—
Product4-[(2-{[4-(1,3-Thiazol-2-yl)phenyl]oxy}ethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11719767—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-a98d4376f9f8417c89f4c1e4d16c1410
Source noteValidation data from https://doi.org/10.1039/C8SC04228D