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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951219Generated: October 27, 2026

Hydrochloric Acid → 2-[7-hydroxy-7-(2-methoxyphenyl)-2-[2-(2-phenylmethoxyphenyl)acetyl]-3,3a,4,5,6,7a-hexahydro-1H-isoindol-5-yl]acetonitrile

https://huagongshe.com/reaction/951219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant(2-Benzyloxyphenyl)acetic acidHCID 519916—
Reactant2-[7-Hydroxy-7-(2-methoxyphenyl)-1,2,3,3a,4,5,6,7a-octahydroisoindol-5-yl]acetonitrileHCID 18931546—
ReactantHCID 178418300HCID 178418300—
Product2-[7-hydroxy-7-(2-methoxyphenyl)-2-[2-(2-phenylmethoxyphenyl)acetyl]-3,3a,4,5,6,7a-hexahydro-1H-isoindol-5-yl]acetonitrileHCID 178489433—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d622ed4c0e524b098c9adacf625bb37f
Source noteValidation data from https://doi.org/10.1039/C8SC04228D