2-Chloro-1-phenylethanol → N-[3-[1-(2-hydroxy-2-phenylethyl)piperidin-4-yl]phenyl]-2-methylpropanamide
Reaction equation
[CH3:11][CH:12]([C:13](=[O:14])[NH:15][c:16]1[cH:17][c:18]([CH:22]2[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]2)[cH:19][cH:20][cH:21]1)[CH3:28].[Cl:1][CH2:2][CH:3]([OH:4])[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1>>[CH2:2]([CH:3]([OH:4])[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[N:25]1[CH2:24][CH2:23][CH:22]([c:18]2[cH:17][c:16]([NH:15][C:13]([CH:12]([CH3:11])[CH3:28])=[O:14])[cH:21][cH:20][cH:19]2)[CH2:27][CH2:26]1Participants
3
Sources & evidence
- ORD record
- ord-a2a263b8dd544522b1100cd70961b602
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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