4-Cyanophenylboronic acid → Tert-butyl 4'-cyano-2-methyl-1,1'-biphenyl-4-carboxylate

HRID 951253Notes

Reaction equation

HRID 951253 reaction equation
[Br:1][c:2]1[c:3]([CH3:15])[cH:4][c:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[cH:13][cH:14]1.[Br:27][CH2:28][c:29]1[cH:30][c:31]([O:32][CH3:33])[cH:34][cH:35][c:36]1-[c:37]1[cH:38][cH:39][c:40]([Cl:41])[cH:42][cH:43]1.[C:16](#[N:17])[c:18]1[cH:19][cH:20][c:21]([B:24]([OH:25])[OH:26])[cH:22][cH:23]1>>[c:2]1(-[c:21]2[cH:20][cH:19][c:18]([C:16]#[N:17])[cH:23][cH:22]2)[c:3]([CH3:15])[cH:4][c:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 27343264-Cyanophenylboronic acidHCID 11845988Tert-butyl 4-bromo-3-methylbenzoateHCID 219433382-(Bromomethyl)-4'-chloro-4-methoxy-1,1'-biphenyl

Product 1

HCID 22660788Tert-butyl 4'-cyano-2-methyl-1,1'-biphenyl-4-carboxylate

Sources & evidence

ORD record
ord-00edc15dc1f34a22b41fdc6c5979e6db
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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