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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951437Generated: October 30, 2026

1,2-Dichloroethane → 6-[4-[[3-[3-(Trifluoromethyl)phenyl]piperidin-1-yl]methyl]phenoxy]pyridine-3-carboxamide

https://huagongshe.com/reaction/951437

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant3-[3-(Trifluoromethyl)phenyl]piperidineHCID 3049031—
Reactant6-(4-Formylphenoxy)pyridine-3-carboxamideHCID 56851422—
Product6-[4-[[3-[3-(Trifluoromethyl)phenyl]piperidin-1-yl]methyl]phenoxy]pyridine-3-carboxamideHCID 59730087—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d6dea899f5c44a75bcd0272ef205e56b
Source noteValidation data from https://doi.org/10.1039/C8SC04228D