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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951551Generated: November 1, 2026

Trifluoroacetic acid → racemic (2'R,3R,4'S)-1'-[3-(4-acetylamino-piperidin-1-yl)-propyl]-6-chloro-4'-(3-chlorophenyl)-2'-isopropenyl spiro[3H-indole-3,3' piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/951551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-AcetamidopiperidineHCID 1445156—
Reactant(1-Methoxyethyl)(trimethyl)silaneHCID 22400412—
Reactant6-chloro-4'-(3-chlorophenyl)-1'-(3-chloropropyl)-6'-prop-1-en-2-ylspiro[1H-indole-3,5'-piperidine]-2,2'-dioneHCID 77580065—
Productracemic (2'R,3R,4'S)-1'-[3-(4-acetylamino-piperidin-1-yl)-propyl]-6-chloro-4'-(3-chlorophenyl)-2'-isopropenyl spiro[3H-indole-3,3' piperidine]-2,6'(1H)-dioneHCID 76567943—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-28ba062c5e5640548496b50eaef84626
Source noteValidation data from https://doi.org/10.1039/C8SC04228D