Sodium ion → {2-[2-(2-Hydroxy-ethoxy)-benzylamino]-5-prop-2-ynyloxy-phenyl}-(4-isopropyl-phenyl)-methanone

HRID 951641Notes

Reaction equation

HRID 951641 reaction equation
[C:35]([O:36][BH-:37]([O:38][C:39](=[O:40])[CH3:41])[O:42][C:43](=[O:44])[CH3:45])(=[O:46])[CH3:47].[Cl:49][CH2:50][Cl:51].[NH2:1][c:2]1[c:3]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([CH:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH2:9][C:10]#[CH:11])[cH:6][cH:7]1.[Na+:48].[OH2:52].[OH:23][CH2:24][CH2:25][O:26][c:27]1[c:28]([CH:29]=[O:30])[cH:31][cH:32][cH:33][cH:34]1>>[NH:1]([c:2]1[c:3]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([CH:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH2:9][C:10]#[CH:11])[cH:6][cH:7]1)[CH2:29][c:28]1[c:27]([O:26][CH2:25][CH2:24][OH:23])[cH:34][cH:33][cH:32][cH:31]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6344DichloromethaneHCID 939892-(2-Hydroxyethoxy)benzaldehydeHCID 2724942TriacetoxyborohydrideHCID 45139628(2-Amino-5-(prop-2-yn-1-yloxy)phenyl)(4-isopropylphenyl)methanone

Product 1

HCID 10433518{2-[2-(2-Hydroxy-ethoxy)-benzylamino]-5-prop-2-ynyloxy-phenyl}-(4-isopropyl-phenyl)-methanone

Sources & evidence

ORD record
ord-81d123852ada4288b75ea72d56c1e51a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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