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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 951653Generated: October 30, 2026

1,2-Dichloroethane → 5-[(1H-Indol-4-ylmethyl)-carbamoyl]-3-trifluoromethyl-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/951653

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant(1H-indol-4-yl)methanamineHCID 280302—
Reactant5-(Methoxycarbonyl)-4-(trifluoromethyl)thiophene-2-carboxylic acidHCID 68226602—
Product5-[(1H-Indol-4-ylmethyl)-carbamoyl]-3-trifluoromethyl-thiophene-2-carboxylic acid methyl esterHCID 68226931—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9f373d96f73741178f9286e08a5f8eae
Source noteValidation data from https://doi.org/10.1039/C8SC04228D