Dichloromethane → (4-Fluorophenyl)-2-thiazolylmethanone

HRID 951685Notes

Reaction equation

[CH3:11][Si:12]([c:13]1[s:14][cH:15][cH:16][n:17]1)([CH3:18])[CH3:19].[Cl:20][CH2:21][Cl:22].[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[Cl:8])[cH:9][cH:10]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[c:13]2[s:14][cH:15][cH:16][n:17]2)[cH:9][cH:10]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 678794-Fluorobenzoyl chloride

HCID 5884532-Trimethylsilylthiazole

Product 1

HCID 2758956(4-Fluorophenyl)-2-thiazolylmethanone

Sources & evidence

ORD record: ord-48aef34c19e848b9adafd63f5dced97e
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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