Methanol → 2-[2-(2,2,2-Trifluoroethyl)guanidino]-4-[2-(3-methylthioureido)ethylthiomethyl]thiazole
Reaction equation
[CH3:1][N:2]=[C:3]=[S:4].[CH3:24][OH:25].[F:5][C:6]([CH2:7][N:8]=[C:9]([NH:10][c:11]1[s:12][cH:13][c:14]([CH2:16][S:17][CH2:18][CH2:19][NH2:20])[n:15]1)[NH2:21])([F:22])[F:23]>>[CH3:1][NH:2][C:3](=[S:4])[NH:20][CH2:19][CH2:18][S:17][CH2:16][c:14]1[cH:13][s:12][c:11]([NH:10][C:9](=[N:8][CH2:7][C:6]([F:5])([F:22])[F:23])[NH2:21])[n:15]1Participants
4
Sources & evidence
- ORD record
- ord-709434c08ce44b44b3dd9fad56952bbf
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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