Methanol → tert-butyl 4-[[4-methyl-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]pyrrolidine-3-carbonyl]amino]piperidine-1-carboxylate

HRID 951870Notes

Reaction equation

HRID 951870 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]2)([CH2:30][C:31](=[O:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[CH:11]([CH3:13])[CH2:12]1.[CH3:38][OH:39].[OH-:40].[OH-:42].[Pd+2:41]>>[NH:8]1[CH2:9][C:10]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]2)([CH2:30][C:31](=[O:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[CH:11]([CH3:13])[CH2:12]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 178430269HCID 178430269, compound

Product 1

HCID 178430220tert-butyl 4-[[4-methyl-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]pyrrolidine-3-carbonyl]amino]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-2b5a356b5e864e24980886880a3826a9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…