Methanol → 2-(3,5-Bis(trifluoromethyl)phenyl)propanoic acid

HRID 951981Notes

Reaction equation

HRID 951981 reaction equation
[CH3:23][OH:24].[CH3:3][CH:4]([C:5](=[O:6])[O:7][CH3:8])[c:9]1[cH:10][c:11]([C:19]([F:20])([F:21])[F:22])[cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]1.[Na+:2].[OH-:1]>>[CH3:3][CH:4]([C:5](=[O:6])[OH:7])[c:9]1[cH:10][c:11]([C:19]([F:20])([F:21])[F:22])[cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 21955130(RS)-Methyl alpha-Methyl-3,5-bis(trifluoromethyl)benzeneacetate

Product 1

HCID 115220582-(3,5-Bis(trifluoromethyl)phenyl)propanoic acid

Sources & evidence

ORD record
ord-d773ecb7fd144728b8fe6ed10381aa2c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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