Sodium ion → 3,5-Dichloro-4-(chloromethyl)pyridine

HRID 952058Notes

Reaction equation

[C:15](=[O:16])([O-:17])[O-:18].[Cl:21][CH2:22][Cl:23].[Cl:5][c:6]1[cH:7][n:8][cH:9][c:10]([Cl:14])[c:11]1[CH2:12][OH:13].[Na+:19].[Na+:20].[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][CH2:12][c:11]1[c:6]([Cl:5])[cH:7][n:8][cH:9][c:10]1[Cl:14]

Participants

Reactant 5

HCID 923Sodium ion2×

HCID 6344Dichloromethane

HCID 19660Carbonate Ion

HCID 24386Thionyl Chloride

HCID 17855219(3,5-Dichloropyridin-4-yl)methanol

Product 1

HCID 226268533,5-Dichloro-4-(chloromethyl)pyridine

Sources & evidence

ORD record: ord-c11df1eed4174b7e91613a2d3173ac09
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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