5-Ethynylpyridin-2-amine → 5-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridin-2-ylamine

HRID 952332Notes

Reaction equation

HRID 952332 reaction equation
[C:19](#[CH:20])[c:21]1[cH:22][cH:23][c:24]([NH2:27])[n:25][cH:26]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[I:18])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[C:20]#[C:19][c:21]2[cH:22][cH:23][c:24]([NH2:27])[n:25][cH:26]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 219548275-Ethynylpyridin-2-amineHCID 670013225-(4-Chloro-phenyl)-3-iodo-7-methyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 670005725-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridin-2-ylamine

Sources & evidence

ORD record
ord-e4c21ed5cd864f30923c82f326d0efd1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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