4-Chloroquinoline → trans-[4-(Quinolin-4-ylcarbamoyl)-cyclohexyl]-carbamic acid tert-butyl ester
Reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17]([NH:18][CH:19]1[CH2:20][CH2:21][CH:22]([C:25]([NH2:26])=[O:27])[CH2:23][CH2:24]1)=[O:28].[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12>>[c:2]1([NH:26][C:25]([CH:22]2[CH2:21][CH2:20][CH:19]([NH:18][C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:28])[CH2:24][CH2:23]2)=[O:27])[cH:3][cH:4][n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-66085fa53c994fc9bf5928671c4ed032
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…