Methanol → 4-[2-Fluoro-4-(3-hydroxypropyl)anilino]-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide

HRID 952425Notes

Reaction equation

HRID 952425 reaction equation
[CH3:30][OH:31].[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[NH:15][O:16][CH2:17][CH2:18][OH:19])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:20][cH:21][c:22]([C:24]#[C:25][CH2:26][OH:27])[cH:23]1.[H:28][H:29]>>[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[NH:15][O:16][CH2:17][CH2:18][OH:19])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:20][cH:21][c:22]([CH2:24][CH2:25][CH2:26][OH:27])[cH:23]1

Participants

4

Reactant 3

HCID 887MethanolHCID 111996954-[2-fluoro-4-(3-hydroxy-1-propynyl)anilino]-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamideHCID 178418361HCID 178418361, compound

Product 1

HCID 113035054-[2-Fluoro-4-(3-hydroxypropyl)anilino]-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide

Sources & evidence

ORD record
ord-c4540e9efd10490c89e71bb19dd1a18c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…