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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 952607Generated: October 30, 2026

Dimethyl Sulfoxide → 2-(4-Trifluoromethyl-benzylamino-methyl)-2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-one

https://huagongshe.com/reaction/952607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantWaterHCID 962—
Reactant4-(Trifluoromethyl)benzylamineHCID 76804—
Reactant(8-Oxo-2,3,7,9-tetrahydro-[1,4]dioxino[2,3-e]indol-2-yl)methyl 4-methylbenzenesulfonateHCID 15381105—
Product2-(4-Trifluoromethyl-benzylamino-methyl)-2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-oneHCID 9976915—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3f840e93aec746c1b0281d64c9502d8c
Source noteValidation data from https://doi.org/10.1039/C8SC04228D