2-Aminopyrimidine-5-boronic acid, pinacol ester → 5-{1-[4-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-1H-imidazol-4-yl}-pyrimidin-2-ylamine
Reaction equation
[I:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][c:9](-[c:17]3[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]2)[cH:6]1.[NH2:27][c:28]1[n:29][cH:30][c:31]([B:34]2[O:35][C:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[O:42]2)[cH:32][n:33]1>>[c:2]1(-[c:31]2[cH:30][n:29][c:28]([NH2:27])[n:33][cH:32]2)[n:3][cH:4][n:5](-[c:7]2[n:8][c:9](-[c:17]3[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]2)[cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-7e1fb95aadf44fbf94a9694bc65ee66f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…