7-Bromo-4-(trifluoromethyl)benzofuran → Tert-butyl 2-ethyl-4-[4-(trifluoromethyl)-1-benzofuran-7-yl]piperazine-1-carboxylate

HRID 952799Notes

Reaction equation

HRID 952799 reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH:23]([CH2:28][CH3:29])[CH2:24][NH:25][CH2:26][CH2:27]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([Br:12])[c:7]2[c:8]1[cH:9][cH:10][o:11]2)([F:13])[F:14]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([N:25]2[CH2:24][CH:23]([CH2:28][CH3:29])[N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:27][CH2:26]2)[c:7]2[c:8]1[cH:9][cH:10][o:11]2)([F:13])[F:14]

Participants

3

Reactant 2

HCID 121147077-Bromo-4-(trifluoromethyl)benzofuranHCID 18004789tert-Butyl 2-ethylpiperazine-1-carboxylate

Product 1

HCID 18004790Tert-butyl 2-ethyl-4-[4-(trifluoromethyl)-1-benzofuran-7-yl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-81586c1a6a204f9785ab84559588bba5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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