Dichloromethane → 3{[Bis-(3-methyl-pyridin-2-ylmethyl)-amino]-methyl}-azetidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:12][NH:13][CH2:14][c:15]2[n:16][cH:17][cH:18][cH:19][c:20]2[CH3:21])[CH2:11]1.[CH3:22][c:23]1[c:24]([CH:29]=[O:30])[n:25][cH:26][cH:27][cH:28]1.[Cl:31][CH2:32][Cl:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:12][N:13]([CH2:14][c:15]2[n:16][cH:17][cH:18][cH:19][c:20]2[CH3:21])[CH2:29][c:24]2[c:23]([CH3:22])[cH:28][cH:27][cH:26][n:25]2)[CH2:11]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f5bf6de04a65455691152cebb06b6daf
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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