1,2-Benzoxazole-3-carboxylic acid → tert-butyl 2-[(1,2-benzoxazole-3-carbonylamino)methyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-1-carboxylate

HRID 953142Notes

Reaction equation

HRID 953142 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH:21]2[CH2:22][CH2:23][CH2:24][CH:25]2[CH2:26][CH:27]1[CH2:28][NH2:29].[o:1]1[n:2][c:3]([C:10](=[O:11])[OH:12])[c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[o:1]1[n:2][c:3]([C:10](=[O:12])[NH:29][CH2:28][CH:27]2[N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH:21]3[CH2:22][CH2:23][CH2:24][CH:25]3[CH2:26]2)[c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

3

Reactant 2

HCID 27354451,2-Benzoxazole-3-carboxylic acidHCID 76656761tert-butyl 2-(aminomethyl)-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-1-carboxylate

Product 1

HCID 77195535tert-butyl 2-[(1,2-benzoxazole-3-carbonylamino)methyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-1-carboxylate

Sources & evidence

ORD record
ord-f004a6a892c74a269ff5f4a4b743be45
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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