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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 953153Generated: October 30, 2026

Chloroacetaldehyde → 2-(3-Chloro-propenyl)-6-(4-ethoxy-3-trifluoromethyl-phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile

https://huagongshe.com/reaction/953153

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetaldehydeHCID 33—
ReactantChlorideHCID 312—
ReactantEthanolHCID 702—
ReactantTetrahydrofuranHCID 8028—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
Reactant[4-cyano-6-[4-ethoxy-3-(trifluoromethyl)phenyl]-1H-imidazo[4,5-c]pyridin-2-yl]methyl-triphenylphosphaniumHCID 58938127—
Product2-(3-Chloro-propenyl)-6-(4-ethoxy-3-trifluoromethyl-phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrileHCID 68517725—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-acf20772c2e244a5b3b0d590d01028b4
Source noteValidation data from https://doi.org/10.1039/C8SC04228D