2,4-Dichloro-5-fluoropyrimidine → HCID 22060606, compound

HRID 953351Notes

Reaction equation

HRID 953351 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[NH2:10][c:11]1[cH:12][cH:13][c:14]2[c:19]([cH:20]1)[CH2:18][N:17]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:16][CH2:15]2>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:10][c:11]2[cH:12][cH:13][c:14]3[c:19]([cH:20]2)[CH2:18][N:17]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:16][CH2:15]3)[n:7]1

Participants

3

Reactant 2

HCID 2507052,4-Dichloro-5-fluoropyrimidineHCID 22061016tert-Butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate

Product 1

HCID 22060606HCID 22060606, compound

Sources & evidence

ORD record
ord-9b3c0f21b4f8483987c37f57e06c484b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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