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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 953437Generated: October 25, 2026

Ammonium → tert-Butyl 4-(4-phenyl-3-hydroxy-1-oxobut-1-yl)-4-(2-(tert-butyldimethylsilyloxy)eth-1-yl)piperidine-1-carboxylate

https://huagongshe.com/reaction/953437

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantPhenylacetaldehydeHCID 998—
ReactantTetrahydrofuranHCID 8028—
ReactantHexamethylphosphoramideHCID 12679—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactanttert-Butyl 4-acetyl-4-(2-(tert-butyldimethylsilyloxy)eth-1-yl)piperidine-1-carboxylateHCID 21983972—
Producttert-Butyl 4-(4-phenyl-3-hydroxy-1-oxobut-1-yl)-4-(2-(tert-butyldimethylsilyloxy)eth-1-yl)piperidine-1-carboxylateHCID 21983965—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f5724765185d4f72bff0a5ef4845cb84
Source noteValidation data from https://doi.org/10.1039/C8SC04228D