5-Bromo-2-(4-methylpiperazin-1-yl)pyridine → [8-(4-Methanesulfonyl-phenyl)-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-amine

HRID 953528Notes

Reaction equation

HRID 953528 reaction equation
[Br:25][c:26]1[cH:27][cH:28][c:29]([N:32]2[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]2)[n:30][cH:31]1.[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[c:12]3[n:13]([cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[n:21][c:22]([NH2:24])[n:23]3)[cH:9][cH:10]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[c:12]3[n:13]([cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[n:21][c:22]([NH:24][c:26]2[cH:27][cH:28][c:29]([N:32]4[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]4)[n:30][cH:31]2)[n:23]3)[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 164142065-Bromo-2-(4-methylpiperazin-1-yl)pyridineHCID 674814178-(4-Methanesulfonyl-phenyl)-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Product 1

HCID 59612526[8-(4-Methanesulfonyl-phenyl)-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-amine

Sources & evidence

ORD record
ord-c04f76989d8e44d0afc85331cd31209d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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