Methyl 2-(4-hydroxyphenoxy)acetate → (4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethoxy}-phenoxy)-acetic acid methyl ester

HRID 953613Notes

Reaction equation

HRID 953613 reaction equation
[CH3:28][O:29][C:30]([CH2:31][O:32][c:33]1[cH:34][cH:35][c:36]([OH:39])[cH:37][cH:38]1)=[O:40].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([CH2:14][OH:15])[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[cH:22][c:23]([F:27])[c:24]([F:26])[cH:25]3)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([CH2:14][O:15][c:36]2[cH:35][cH:34][c:33]([O:32][CH2:31][C:30]([O:29][CH3:28])=[O:40])[cH:38][cH:37]2)[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[cH:22][c:23]([F:27])[c:24]([F:26])[cH:25]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 602731Methyl 2-(4-hydroxyphenoxy)acetateHCID 666193102-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethanol

Product 1

HCID 66619469(4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethoxy}-phenoxy)-acetic acid methyl ester

Sources & evidence

ORD record
ord-f79cbb7c0a204a179005f617fdb67df3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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