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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 953618Generated: October 31, 2026

Water → Methyl 5-[4-(difluoromethoxy)phenyl]-1-[(1,1-dioxidothiomorpholin-4-yl)carbonyl]piperidine-3-carboxylate

https://huagongshe.com/reaction/953618

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantEthyl AcetateHCID 8857—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-Nitrophenyl thiomorpholine-4-carboxylate 1,1-dioxideHCID 58116541—
ReactantMethyl 5-[4-(difluoromethoxy)phenyl]piperidine-3-carboxylateHCID 58116573—
ProductMethyl 5-[4-(difluoromethoxy)phenyl]-1-[(1,1-dioxidothiomorpholin-4-yl)carbonyl]piperidine-3-carboxylateHCID 58116465—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-ec09ff38518a42d7b6cca0bcd98fca40
Source noteValidation data from https://doi.org/10.1039/C8SC04228D