Water → (4-(Chloromethyl)piperidin-1-yl)(phenyl)methanone

HRID 953706Notes

Reaction equation

HRID 953706 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[N:9]1[CH2:10][CH2:11][CH:12]([CH2:15][OH:16])[CH2:13][CH2:14]1.[CH:21]([Cl:22])([Cl:23])[Cl:24].[OH2:25].[S:17]([Cl:18])([Cl:19])=[O:20]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[N:9]1[CH2:10][CH2:11][CH:12]([CH2:15][Cl:19])[CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 962WaterHCID 6212ChloroformHCID 24386Thionyl ChlorideHCID 102628704-Piperidinemethanol, 1-benzoyl-

Product 1

HCID 11118098(4-(Chloromethyl)piperidin-1-yl)(phenyl)methanone

Sources & evidence

ORD record
ord-daafe2ef5b63404dab0c611601fce54f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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