Tetrahydro-N-methylthiophen-3-amine 1,1-dioxide → 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (1,1-dioxo-tetrahydro-thiophen-3-yl)-methyl-amide

HRID 953714Notes

Reaction equation

HRID 953714 reaction equation
[O:23]=[S:24]1(=[O:31])[CH2:25][CH:26]([NH:29][CH3:30])[CH2:27][CH2:28]1.[nH:1]1[n:2][cH:3][c:4](-[c:6]2[cH:7][c:8]3[c:9]([cH:21][cH:22]2)-[c:10]2[n:11][c:12]([C:18](=[O:19])[OH:20])[s:13][c:14]2[CH2:15][CH2:16][O:17]3)[cH:5]1>>[n:1]1[nH:2][cH:3][c:4](-[c:6]2[cH:7][c:8]3[c:9]([cH:21][cH:22]2)-[c:10]2[n:11][c:12]([C:18](=[O:20])[N:29]([CH:26]4[CH2:25][S:24](=[O:23])(=[O:31])[CH2:28][CH2:27]4)[CH3:30])[s:13][c:14]2[CH2:15][CH2:16][O:17]3)[cH:5]1

Participants

3

Reactant 2

HCID 2736805Tetrahydro-N-methylthiophen-3-amine 1,1-dioxideHCID 582038838-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid

Product 1

HCID 582037988-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (1,1-dioxo-tetrahydro-thiophen-3-yl)-methyl-amide

Sources & evidence

ORD record
ord-91fefbc258cc402bbfb4b98ebfb4ca3f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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