2-[[2-(3,5-Difluorophenyl)acetyl]amino]propanoic acid → N-(2-benzyl-3-oxo-1,4-dihydroisoquinolin-4-yl)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanamide

HRID 953785Notes

Reaction equation

HRID 953785 reaction equation
[F:1][c:2]1[cH:3][c:4]([CH2:9][C:10](=[O:11])[NH:12][CH:13]([CH3:14])[C:15](=[O:16])[OH:17])[cH:5][c:6]([F:8])[cH:7]1.[NH2:18][CH:19]1[C:20](=[O:36])[N:21]([CH2:29][c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][c:28]21>>[F:1][c:2]1[cH:3][c:4]([CH2:9][C:10](=[O:11])[NH:12][CH:13]([CH3:14])[C:15](=[O:17])[NH:18][CH:19]2[C:20](=[O:36])[N:21]([CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][c:28]32)[cH:5][c:6]([F:8])[cH:7]1

Participants

3

Reactant 2

HCID 219429782-[[2-(3,5-Difluorophenyl)acetyl]amino]propanoic acidHCID 223124384-Amino-2-benzyl-1,2-dihydroisoquinolin-3(4H)-one

Product 1

HCID 10116498N-(2-benzyl-3-oxo-1,4-dihydroisoquinolin-4-yl)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanamide

Sources & evidence

ORD record
ord-58d2d5fefb8f4bcf8eeb65199d17befd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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