Sodium ion → 4-(5-Hydroxymethyl-3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[BH4-:26].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([CH:24]=[O:25])[cH:18][c:19]2[C:20]([F:21])([F:22])[F:23])[CH2:12][CH2:13]1.[Na+:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([CH2:24][OH:25])[cH:18][c:19]2[C:20]([F:21])([F:22])[F:23])[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-e59273a874be4e289e89c0f3ae3294f2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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