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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 953908Generated: October 27, 2026

Tetrahydrofuran → (RS)-[4-(tert-butyl-diphenyl-silanyloxy)-2,6-difluoro-phenyl]-hydroxy-acetic acid ethyl ester

https://huagongshe.com/reaction/953908

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl oxoacetateHCID 70211—
ReactantTert-butyl-(3,5-difluoro-phenoxy)-diphenyl-silaneHCID 21905446—
ReactantButyllithiumHCID 178418339—
Product(RS)-[4-(tert-butyl-diphenyl-silanyloxy)-2,6-difluoro-phenyl]-hydroxy-acetic acid ethyl esterHCID 69291129—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4d5a74d5e85d4e51a4222194e74c3c23
Source noteValidation data from https://doi.org/10.1039/C8SC04228D