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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 953954Generated: November 1, 2026

1,2-Dichloroethane → (+/-)-6-[4-(3-Phenyl-piperidin-1-ylmethyl)-phenoxy]-nicotinamide

https://huagongshe.com/reaction/953954

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
Reactant3-PhenylpiperidineHCID 107207—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant6-(4-Formylphenoxy)pyridine-3-carboxamideHCID 56851422—
Product(+/-)-6-[4-(3-Phenyl-piperidin-1-ylmethyl)-phenoxy]-nicotinamideHCID 59730382—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-6b36567834a6486594c3b3173b4a8a24
Source noteValidation data from https://doi.org/10.1039/C8SC04228D