4-Fluoro-2-(trifluoromethyl)benzyl bromide → 1-[4-Fluoro-2-(trifluoromethyl)benzyl]-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one
Reaction equation
[CH:1]12[CH:2]([N:11]3[NH:12][C:13]([CH3:16])([CH3:17])[C:14]3=[O:15])[CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2.[F:18][c:19]1[cH:20][c:21]([C:27]([F:28])([F:29])[F:30])[c:22]([CH2:23][Br:24])[cH:25][cH:26]1>>[CH:1]12[CH:2]([N:11]3[N:12]([CH2:23][c:22]4[c:21]([C:27]([F:28])([F:29])[F:30])[cH:20][c:19]([F:18])[cH:26][cH:25]4)[C:13]([CH3:16])([CH3:17])[C:14]3=[O:15])[CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2Participants
3
Sources & evidence
- ORD record
- ord-0a37a0a6670f4480a09c4b8bd3283403
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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