3-Fluoro-4-hydroxybenzeneacetic acid → N-[[1-[(2,3-dichlorophenyl)methyl]pyrrolidin-3-yl]methyl]-2-(3-fluoro-4-hydroxyphenyl)acetamide
Reaction equation
[F:1][c:2]1[cH:3][c:4]([CH2:9][C:10](=[O:11])[OH:12])[cH:5][cH:6][c:7]1[OH:8].[NH2:13][CH2:14][CH:15]1[CH2:16][CH2:17][N:18]([CH2:19][c:20]2[cH:21][cH:22][c:23]([Cl:24])[c:25]([Cl:26])[cH:27]2)[CH2:28]1.[NH2:29][CH2:30][CH:31]1[CH2:32][N:33]([CH2:36][c:37]2[c:38]([Cl:44])[c:39]([Cl:43])[cH:40][cH:41][cH:42]2)[CH2:34][CH2:35]1>>[F:1][c:2]1[cH:3][c:4]([CH2:9][C:10](=[O:12])[NH:29][CH2:30][CH:31]2[CH2:32][N:33]([CH2:36][c:37]3[c:38]([Cl:44])[c:39]([Cl:43])[cH:40][cH:41][cH:42]3)[CH2:34][CH2:35]2)[cH:5][cH:6][c:7]1[OH:8]Participants
4
Sources & evidence
- ORD record
- ord-2d78e680448d495fa2502de6651f683e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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