Acetone → N-[5-(1-hydroxy-2-iodoethyl)-2-phenylmethoxyphenyl]methanesulfonamide

HRID 954143Notes

Reaction equation

HRID 954143 reaction equation
[Br:1][CH2:2][CH:3]([OH:4])[c:5]1[cH:6][c:7]([NH:19][S:20](=[O:21])(=[O:22])[CH3:23])[c:8]([O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:9][cH:10]1.[CH3:26][C:27](=[O:28])[CH3:29].[I-:24].[Na+:25]>>[CH2:2]([CH:3]([OH:4])[c:5]1[cH:6][c:7]([NH:19][S:20](=[O:21])(=[O:22])[CH3:23])[c:8]([O:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:9][cH:10]1)[I:24]

Participants

5

Reactant 4

HCID 180AcetoneHCID 923Sodium ionHCID 30165Iodide IonHCID 22220535n-[2-Benzyloxy-5-(2-bromo-1-hydroxy-ethyl)-phenyl]-methanesulfonamide

Product 1

HCID 19073108N-[5-(1-hydroxy-2-iodoethyl)-2-phenylmethoxyphenyl]methanesulfonamide

Sources & evidence

ORD record
ord-b88fc8478ce84f929667a3d2bd67c944
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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